CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题：Treatment horizon in multiple myeloma.
Treatment horizon in multiple myeloma.
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旨在解决 MM 相关免疫功能障碍的新疗法的出现，带来了总生存期的改善。
回顾多发性骨髓瘤（MM）现有及新兴治疗方法。
叙述性综述。
MM是一种复杂且异质性明显的疾病，近年来治疗方法的数量和范围不断扩大。多种新疗法正在研发中，包括改良单克隆抗体、抗体药物偶联物、双特异性T细胞衔接器和CAR-T 细胞疗法。
旨在应对MM相关免疫功能障碍的新疗法不断涌现，已推动总生存期改善。
This paper reviews current and emerging therapies for multiple myeloma (MM).
Narrative review.
MM is a complex, heterogenous condition, and in recent years there has been an expansion in the number and range of treatments. Several new treatment approaches, including enhanced monoclonal antibodies, antibody-drug conjugates, bispecific T-cell engagers, and chimeric antigen-T-cell therapy are under development.
The emergence of new treatments that aim to tackle MM-associated immune dysfunction has led to improvements in overall survival.
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