CAR-T（CAR-T）细胞疗法在非肿瘤性疾病中的应用
Chimeric antigen receptor T (CAR-T) cell therapy in non-oncological diseases.
CAR-T（CAR-T）细胞在血液系统恶性肿瘤中的应用推动了这种免疫治疗形式的显著进展。
CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
时隐时现：CD19 靶向 CAR-T 细胞治疗后 CD19 阴性弥漫大 B 细胞淋巴瘤的孤立性中枢神经系统复发
英文原题：Now you see me, now you don't: Isolated central nervous system recurrence of CD19-negative diffuse large B-cell lymphoma following CD19-directed CAR T-cell treatment.
查看英文原题
Now you see me, now you don't: Isolated central nervous system recurrence of CD19-negative diffuse large B-cell lymphoma following CD19-directed CAR T-cell treatment.
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中文摘要
作者讨论了一例 CD19 阴性弥漫大 B 细胞淋巴瘤病例；患者接受 CD19 靶向 CAR-T 细胞治疗后出现中枢神经系统复发。肿瘤细胞不表达 CD19，给流式细胞术评估带来了挑战。
展开英文摘要原文
The authors discuss a case of CD19-negative diffuse large B-cell lymphoma with central nervous system relapse following CD19-directed CAR T-cell treatment. Absence of CD19 expression by the tumour cells presented a challenge for flow cytometry evaluation.
论文信息
- 作者
- Gokozan HN、Ouseph MM、Carniello JVS、Besien KV、Patel SS
- 第一作者单位
- Division of Cytopathology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College/NewYork-Presbyterian Hospital, New York, New York, USA.United States
- 通讯作者单位
- Division of Hematopathology, Department of Pathology and Laboratory Medicine, Weill Cornell Medical College/NewYork-Presbyterian Hospital, New York, New York, USA.United States
- 期刊
- Cytopathology : official journal of the British Society for Clinical Cytology2022 Nov
- 原文标识
- PubMed 35713946 · DOI 10.1111/cyt.13160