CELL INTELLIGENCE · 肿瘤细胞治疗研究
肿瘤细胞治疗研究
英文原题：Evolution of Immunotherapy for Ovarian Cancer from a Bird's-Eye Perspective: A Text-Mining Analysis of Publication Trends and Topics.
Evolution of Immunotherapy for Ovarian Cancer from a Bird's-Eye Perspective: A Text-Mining Analysis of Publication Trends and Topics.
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本研究详尽描述了卵巢癌免疫治疗的发展历程，并总结了其过去 20 年的研究趋势。
卵巢肿瘤是最重要的妇科恶性肿瘤之一，预后较差。本研究采用文献计量学方法，识别卵巢癌免疫治疗的研究趋势。
从Web of Science核心引文数据库检索2000至2020年发表的相关文献，并使用VOSviewer和CiteSpace文献计量分析软件进行分析。
共检出2000年1月至2020年12月发表的卵巢癌免疫治疗文章1,729篇，年度发表量逐年增加，从2000年的40篇增至2020年的209篇。文章来自61个国家，其中美国在论文产出、总引用次数和篇均引用次数方面占主导地位。共被引网络揭示14个子主题。“PD-L1表达”“肿瘤反应性TIL”和“PARP抑制剂”是当前潜在子主题。研究还根据时间线分析确定了研究趋势。
本研究全面描述了过去20年卵巢癌免疫治疗的发展并总结其研究趋势。
Ovarian tumors are among the most prominent gynecological malignancies and have a poor prognosis. Immunotherapy has undergone incredible progress in the past two decades. Our study aimed to use a bibliometric approach to identify research trends in ovarian cancer immunotherapy.
Literature on this topic published from 2000-2020 was retrieved from the Web of Science Core Citation database and analyzed using the bibliometric analysis software VOSviewer and CiteSpace.
A total of 1729 articles on ovarian cancer immunotherapy published from January 2000 to December 2020 were identified. The number of published articles increased each year, from 40 in 2000 to 209 in 2020. These publications were from 61 countries, and the USA showed a dominant position in publication output, total citations, and average number of citations per paper. Co-citation networks revealed 14 subtopics. 'PD-L1 expression,' 'tumor reactive til,' and 'parp inhibitor' are the current potential subtopics. Furthermore, we determined research trends according to the timeline analysis.
Our study exhaustively describes the development and summarizes the research trends of ovarian cancer immunotherapy over the past 20 years.
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