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结外 NK/T 细胞淋巴瘤鼻型伴广泛眼组织受累:一例病例报告

英文原题:Extranodal natural killer/T-cell lymphoma nasal type with extensive ocular tissue involvement: a case report.

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Extranodal natural killer/T-cell lymphoma nasal type with extensive ocular tissue involvement: a case report.

PubMed 2021/11/11(内容时间) Diagn Pathol Q1 · IF 3.5(JCR 2025)

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研究概要

结外 NK/T 细胞淋巴瘤,鼻型是一种侵袭性疾病,可能累及广泛眼组织,并导致视力急剧恶化。

中文摘要

报告一例罕见的鼻型结外NK/T细胞淋巴瘤(ENKTL),广泛累及眼部组织,包括结膜、睫状体、玻璃体和视网膜。病例:一名52岁女性曾因右侧鼻腔鼻型ENKTL接受放疗,随后右眼视力急剧恶化。体格及辅助检查显示眼部多处组织受累,包括结膜、睫状体、玻璃体和视网膜。玻璃体标本及结膜活检证实右眼存在鼻型ENKTL。患者接受全身及眼部化疗后,眼部症状显著改善;确诊7个月后全身情况仍稳定。

鼻型结外NK/T细胞淋巴瘤具有侵袭性,可广泛累及眼组织并导致视力急剧下降。应密切观察眼部相关表现,并在确诊后尽早开始积极的联合治疗。

展开英文摘要原文

To report a rare case of extranodal natural killer/T-cell lymphoma (ENKTL), nasal type related to extensive ocular tissue, including conjunctiva, ciliary body, vitreous and retina. CASE PRESENTATION: A 52-year-old woman who had been treated by radiotherapy for ENKTL, nasal type in the right nasal cavity presented with a dramatic deterioration of vision in right eye. Physical and accessory examination showed extensive ocular tissue related, including conjunctiva, ciliary body, vitreous and retina. Vitreous specimen and conjunctiva biopsy revealed the presence of ENKTL, nasal type in the right eye. She was treated with systemic and ophthalmic chemotherapy, her ocular symptoms significantly improved, and systemic condition remained stable 7 months after the diagnosis.

Extranodal natural killer/T-cell lymphoma, nasal type is an aggressive disease and may relate extensive ocular tissue and course dramatic vision deterioration. It is important to observe ocular related and begin aggressive combined therapy as early as possible after diagnosis.

论文信息

作者
Han R、Jiang Y、Bian A、Meng Z、Chen H、Ye J
第一作者单位
Department of Ophthalmology, Peking Union Medical College Hospital, Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, 100730, China.China
通讯作者单位
Department of Ophthalmology, Peking Union Medical College Hospital, Key Laboratory of Ocular Fundus Diseases, Chinese Academy of Medical Sciences, Beijing, 100730, China. yejunjie_xh@163.com.China
文献类型
病例报告
期刊
Diagnostic pathology2021 Nov 11
原文标识
PubMed 34763717 · DOI 10.1186/s13000-021-01167-3