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押注 BRD4 抑制以对抗胶质母细胞瘤中 CAR-T 细胞治疗的适应性耐药

英文原题:BETting on BRD4 inhibition to combat adaptive resistance to CAR T cell therapy in glioblastoma.

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BETting on BRD4 inhibition to combat adaptive resistance to CAR T cell therapy in glioblastoma.

PubMed 2021/09/24(内容时间) Mol Ther Q1 · IF 11.4(JCR 2025)

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论文信息

作者
Hopkins CR、Fraietta JA
第一作者单位
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, South Pavilion Expansion (SPE), Room 9-104, 3400 Civic Center Boulevard, Bldg. 421, Philadelphia, PA 19104-5156, USA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.United States
通讯作者单位
Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, South Pavilion Expansion (SPE), Room 9-104, 3400 Civic Center Boulevard, Bldg. 421, Philadelphia, PA 19104-5156, USA; Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Abramson Cancer Center, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. Electronic address: jfrai@upenn.edu.United States
文献类型
美国 NIH 资助研究 · 非美国政府资助研究 · 评论
期刊
Molecular therapy : the journal of the American Society of Gene Therapy2021 Oct 6
原文标识
PubMed 34559988 · DOI 10.1016/j.ymthe.2021.09.008