基于包被溶瘤病毒的“双重打击”策略在胃肠道肿瘤中触发 CD19 CAR-T 治疗

Coated oncolytic viruses based "double strike" strategy triggering CD19 CAR-T therapy in gastrointestinal tumors.

CAR-T（CAR-T）细胞疗法在实体瘤中的疗效受限于稳定抗原靶点的稀缺。

Claudin18.2-CAR T 细胞治疗转移性胃癌靶病灶完全缓解

Metastatic gastric cancer target lesion complete response with Claudin18.2-CAR T cells.

用患者来源的抗CD19嵌合抗原受体（CAR）T细胞治疗血液系统恶性肿瘤，已证明对于其他治疗难治的晚期白血病和淋巴瘤患者可实现长期缓解。

纳米抗体导向的靶向 CEA 的 CAR-T 细胞清除胃肠道癌异种移植瘤

Nanobody-Directed CEA-Targeting CAR T Cells Eliminate Gastrointestinal Cancer Xenografts.

胃肠道肿瘤（GIC），包括胃癌和结直肠癌，是全球癌症相关死亡的主要原因之一。

胃癌腹膜转移患者腹腔免疫微环境与腹腔化疗疗效

Intraperitoneal immune microenvironment and efficacy of intraperitoneal chemotherapy in patients with gastric cancer and peritoneal metastasis.

2017年至2023年间，前瞻性纳入了30名接受分期腹腔镜检查的患者。

CD19 靶向 CAR-T 细胞治疗后发生胃腺癌

Gastric adenocarcinoma following CD19-directed chimeric antigen receptor T cell therapy.

CD19 CAR T 细胞成功治疗同时性滤泡性淋巴瘤与胃腺癌 1 例并文献复习

Successful treatment of a case with synchronous follicular lymphoma and gastric adenocarcinoma with CD19 CAR T cells and literature review.

已知和目的：抗CD19 CAR-T细胞疗法对B细胞淋巴瘤有效。