利用 CD8 靶向 mRNA-LNP 体内重编程 CD22 CAR-T 细胞以治疗血液系统恶性肿瘤

Reprogramming CD22 CAR-T cells in vivo using CD8-targeted mRNA-LNPs to treat hematological malignancies.

AI 引导的 CAR 设计与靶向通路调控以增强多抗原 CAR-T 细胞持久性并克服抗原逃逸

AI-guided CAR designs and targeted pathway modulation to enhance multi-antigen CAR T cell durability and overcome antigen escape.

IDR 诱导的 CAR 凝聚增强 CAR-T 对低抗原癌症的细胞毒性

IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.

揭示 T 细胞耗竭：对 CAR-T 细胞治疗的启示与意义

Unlocking T cell exhaustion: Insights and implications for CAR-T cell therapy.

儿童、青少年和年轻成人肿瘤学中的 CAR-T 细胞治疗格局——临床试验的综合分析

CAR T-cell therapy landscape in pediatric, adolescent and young adult oncology - A comprehensive analysis of clinical trials.

内部冷冻保存 CAR/TCR-T 细胞流式细胞术质量控制的建立与验证

Establishment and validation of in-house cryopreserved CAR/TCR-T cell flow cytometry quality control.

我们开发并验证了一种可行且可靠的方法，用于建立冷冻保存的 CAR/TCR T 细胞库，作为流式细胞术质量控制品，可作为 CAR/TCR T 细胞产品过程中和批次放行检测的质量控制标准。