肿瘤细胞治疗研究
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Decitabine enhances targeting of AML cells by NY-ESO-1-specific TCR-T cells and promotes the maintenance of effector function and the memory phenotype
这些数据为DAC与NY-ESO-1特异性dTCR-T细胞联合治疗AML提供了临床前证据。
T-cell receptor-engineered T cells (TCR-e T cells): A novel cellular therapy for hematopoietic malignancies?
尽管CAR-T 细胞在治疗多种血液系统恶性肿瘤方面取得了不可否认的成功，但仍存在该疗法效果有限的情况，例如在急性髓系白血病（AML）中。
Downregulation of HLA class II is associated with relapse after allogeneic stem cell transplantation and alters recognition by antigen-specific T cell
白血病细胞中供受者错配 HLA 等位基因的基因组缺失是异基因造血干细胞移植（HSCT）后复发的主要原因。
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