CELL INTELLIGENCE · 肿瘤细胞治疗研究

诊断时 CD70 过表达预测滤泡性淋巴瘤复发并支持 CD19-CD70 双靶点 CAR-T 治疗

CD70 Overexpression at Diagnosis Predicts Relapse and supports dual CD19-CD70 CAR-T Therapy in Follicular Lymphoma.

寻找 AML 中安全有效的 CAR-T 靶点

The search for safe and effective CAR-T targets in AML.

CAR-T 与 CAR NK 细胞治疗急性髓系白血病的最新进展

Recent advances in CAR T and CAR NK cell therapy for AML.

单细胞与 bulk 转录组学揭示预测弥漫大 B 细胞淋巴瘤预后的 CD8⁺ T 细胞基因特征

Single-cell and bulk transcriptomics reveal a CD8(+) T-cell gene signature predicting prognosis in diffuse large B-cell lymphoma.

本研究突出了 DLBCL 中 CD8+ T 细胞的异质性，并建立了一个预后基因特征，可为患者生存预测和 CAR-T 治疗疗效提供信息。

急性髓系白血病 CAR-T 细胞治疗的新兴策略：通过双抗原靶向克服异质性并提高安全性

Emerging strategies in CAR-T cell therapy for acute myeloid leukemia: overcoming heterogeneity and improving safety through dual-antigen targeting.

高危 MCL：识别与治疗

High-risk MCL: recognition and treatment.

敲除 CD70 使 CD70 特异性 NanoCAR T 细胞免于抗原诱导的耗竭

Knocking Out CD70 Rescues CD70-Specific NanoCAR T Cells from Antigen-Induced Exhaustion.

表达 IL-15 的 CD70 特异性 CAR NK 细胞治疗 CD19 阴性 B 细胞恶性肿瘤

CD70-specific CAR NK cells expressing IL-15 for the treatment of CD19-negative B-cell malignancy.

2022 年套细胞淋巴瘤：分子发病机制、风险分层、临床策略及当前与新型治疗的综合更新

Mantle cell lymphoma in 2022-A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatment

通过溶瘤病毒基因治疗同时靶向 CD40/4-1BB 以增强淋巴瘤中 CAR-T 细胞应答

Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy.