CAR T 细胞:改善儿童肿瘤结局所缺失的一环?
CAR T cells: the missing piece needed to improve outcomes for children with cancer?
B 细胞急性淋巴细胞白血病 (B-ALL) 是儿童期最常见的癌症。
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CAR T cells: the missing piece needed to improve outcomes for children with cancer?
B 细胞急性淋巴细胞白血病 (B-ALL) 是儿童期最常见的癌症。
T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape.
双特异性CAR-T 细胞疗法在晚期B细胞恶性肿瘤的临床试验中显示出有希望的结果。
Contemporary management of diffuse large B-cell lymphoma in Japan.
由专家或通过会诊网络对DLBCL进行准确的病理诊断至关重要,而一种新兴的基因组检测将有助于未来的精准诊疗方法。
BL-01, an Fc-bearing, tetravalent CD20 × CD5 bispecific antibody, redirects multiple immune cells to kill tumors in vitro and in vivo.
作者认为,bsAb在体内的疗效归因于Fc对先天免疫的联合激活以及将CIK细胞重定向以杀伤肿瘤靶标。
The effective and safe administration of Epcoritamab in relapsed CD19-CD5+ DLBCL following CAR-T therapy.
该病例凸显了 epcoritamab 联合减瘤治疗用于治疗 CAR-T 难治性 CD19 阴性 DLBCL 的潜力。
Nanobody-derived bispecific CAR-T cell therapy enhances the anti-tumor efficacy of T cell lymphoma treatment.
T 细胞淋巴瘤(TCL)是一组高度异质性的疾病,预后差,5 年总生存率低。
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