CELL INTELLIGENCE · 肿瘤细胞治疗研究

AZD0120（BCMA CAR-T）治疗多发性骨髓瘤：III 期临床试验

A Study Comparing AZD0120, a Dual-targeted CAR-T Against B-cell Maturation Antigen (BCMA) and CD19, Versus Standard Regimens in Participants With Rela

这是一项 III 期、随机的注册临床试验，比较细胞治疗与阳性对照方案在多发性骨髓瘤中的疗效与安全性。研究设计：随机、2 个分组。当前状态：招募中。计划入组 508 例。试验地点：中国 · 北京、长春、长沙、重庆（共 143 个中心，其中中国 27 个）。登记号：NCT07391657。

免疫效应细胞相关肠炎的组织学谱系与 T 细胞克隆性特征

Characterization of Histologic Spectrum and T-Cell Clonality in Immune Effector Cell-Associated Enteritis.

下一代基于抗体的癌症治疗：抗体-药物偶联物和双特异性抗体在血液系统恶性肿瘤和实体瘤中的应用

Next-generation antibody-based therapeutics in cancer: antibody-drug conjugates bispecific antibodies across hematologic malignancies and solid tumors

AML/MDS 细胞治疗的最新进展

Recent advances in cell therapy for AML/MDS.

CD19 与 BCMA 靶向 CAR-T 细胞治疗中输注前宿主骨髓易感性：克隆性造血、血液毒性与治疗相关髓系肿瘤

Pre-Infusion Host-Marrow Vulnerability in CD19- and BCMA-Directed CAR T-Cell Therapy: Clonal Hematopoiesis, Hematotoxicity, and Therapy-Related Myeloi

Idecabtagene Vicleucel 后 100 天内的感染及其对复发/难治性多发性骨髓瘤生存的影响：一项 CIBMTR 分析

Infections Within 100 Days of Idecabtagene Vicleucel and Impact on Survival for Relapsed/Refractory Multiple Myeloma: A CIBMTR Analysis.

BCMA/CD19 双靶向 CAR-T 细胞疗法用于新诊断多发性骨髓瘤老年患者：一项 1 期研究

BCMA/CD19 dual-targeting CAR T-cell therapy in older patients with newly diagnosed multiple myeloma: a phase 1 study.

CAR-T 细胞治疗前基于苯达莫司汀的淋巴细胞清除：一项系统综述

Bendamustine-based lymphodepletion prior to CAR T-cell therapy: a systematic review.

RN1201 注射液一线治疗新诊断多发性骨髓瘤的安全性和疗效

Safety and Efficacy of RN1201 Injection as First-Line Treatment for Newly Diagnosed Multiple Myeloma

这是一项 I 期注册临床试验，评估异体 CAR-T 细胞治疗多发性骨髓瘤的疗效与安全性。当前状态：招募中。计划入组 18 例。试验地点：中国 · 苏州（共 1 个中心，其中中国 1 个）。登记号：NCT07652138。

多发性骨髓瘤中的单特异性和双特异性嵌合抗原受体（CAR）T 细胞治疗：系统综述、荟萃分析与荟萃回归

Monospecific and Bispecific Chimeric Antigen Receptor (CAR) T-cell Therapy in Multiple Myeloma: A Systematic Review, Meta-analysis and Meta-regression