多发性骨髓瘤中的双抗原靶向 T 细胞免疫治疗:规避肿瘤异质性和预防抗原逃逸
Dual-antigen-targeting T-cell immunotherapies in MM: circumventing tumor heterogeneity and preventing antigen escape.
双靶向最终应在大规模 III 期试验中,与靶点转换的单靶向药物序贯治疗这一经典方案进行比较。
ALL SOURCES
Dual-antigen-targeting T-cell immunotherapies in MM: circumventing tumor heterogeneity and preventing antigen escape.
双靶向最终应在大规模 III 期试验中,与靶点转换的单靶向药物序贯治疗这一经典方案进行比较。
Novel immunotargets in multiple myeloma: biological relevance and therapeutic potential.
多发性骨髓瘤是一种血液系统恶性肿瘤,其特征是复杂的遗传和微环境因素驱动疾病进展和治疗耐药。
Navigating the Post-BCMA/GPRC5D Landscape: Efficacy of Selinexor, Bortezomib, and Dexamethasone After Sequential Immunotherapy Failure in Penta-Refrac
总体缓解率(ORR)为61%,包括1例完全缓解、5例非常好的部分缓解和5例部分缓解,中位无进展生存期(PFS)为4.3个月。
Bispecific antibodies targeting BCMA or GPRC5D are highly effective in relapsed myeloma after CAR T-cell therapy.
这些结果提示,双特异性抗体可作为复发/难治性多发性骨髓瘤(RRMM)患者 CAR-T 细胞治疗后复发的标准治疗。
Poor outcomes with BCMA-targeting bispecific antibodies following early relapse from ide-cel: a real-world French study.
抗BCMA BsAb疗效有限,而非BCMA BsAb可能在ide-cel早期复发后提供一种有前景的治疗方法。
Patient selection for CAR T or BiTE therapy in multiple myeloma: Which treatment for each patient?
多发性骨髓瘤(MM)是一种浆细胞恶性肿瘤,全球受累患者数量不断增加。
Beyond the marrow: insights from comprehensive next-generation sequencing of extramedullary multiple myeloma tumors.
本研究是迄今为止对EMM肿瘤(N = 14)最全面的下一代测序分析,揭示了关键分子特征并描述了肿瘤微环境。
The evolution of bispecific antibodies in multiple myeloma.
多发性骨髓瘤(MM)的治疗在过去十年中发生了革命性变化,随着靶向CD38的单克隆抗体如达雷妥尤单抗和伊沙妥昔单抗的问世,这些药物已被整合到新诊断或复发和/或难治性(R/R)MM患者的治疗武器库中。
SOHO State of the Art Updates and Next Questions | Treatment of Myeloma Early Relapse: Non-CAR T Cell.
早期复发多发性骨髓瘤的治疗应个体化,以优化患者结局,并在可接受的毒性特征下实现长期缓解。
Promising Antigens for the New Frontier of Targeted Immunotherapy in Multiple Myeloma.
近年来多发性骨髓瘤(MM)治疗中新型药物的纳入改善了患者的临床结局。
共 10 条
MEMBER ACCOUNT
登录成功会直接打开下一页。