接头 CAR 共表达在淋巴瘤单一及双重抗原丢失后保留 CAR-T 细胞疗效
Co-expression of an adapter CAR retains efficacy of CAR T cells after single and dual antigen loss in lymphoma.
CAR-T 细胞疗法对许多 B 细胞恶性肿瘤患者有效,但抗原逃逸是导致疗效减弱或丧失的主要耐药机制。
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Co-expression of an adapter CAR retains efficacy of CAR T cells after single and dual antigen loss in lymphoma.
CAR-T 细胞疗法对许多 B 细胞恶性肿瘤患者有效,但抗原逃逸是导致疗效减弱或丧失的主要耐药机制。
Preclinical development of three novel CARs targeting CD79b for the treatment of non-Hodgkin's lymphoma and characterization of the loss of the target
基于特异性、疗效和靶抗原丢失,CARLY3 代表了一种针对非霍奇金淋巴瘤的潜在新型 CAR 治疗。
ARI0003: Co-transduced CD19/BCMA dual-targeting CAR-T cells for the treatment of non-Hodgkin lymphoma.
CD19 CAR-T 疗法在复发/难治性非霍奇金淋巴瘤(NHL)中已取得显著缓解。
The role of chimeric antigen receptor T cells targeting more than one antigen in the treatment of B-cell malignancies.
几种靶向CD19的CAR-T 细胞(CART19)产品已被批准用于治疗复发/难治性非霍奇金淋巴瘤(NHL)和急性淋巴细胞白血病(ALL)患者。
Chimeric Antigen Receptor-T Cell Therapy for Lymphoma: New Settings and Future Directions.
在过去十年中,抗CD19 CAR-T细胞疗法引领了B细胞非霍奇金淋巴瘤治疗模式的转变,最初获批用于复发/难治性(R/R)大B细胞淋巴瘤,随后获批用于R/R套细胞淋巴瘤和滤泡性淋巴瘤。
CAR-T Cell Therapy in Large B Cell Lymphoma.
大 B 细胞淋巴瘤(LBCL)是最常见的非霍奇金淋巴瘤之一(约占 30%)。
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