代谢依赖性与神经祖细胞失调:儿童高级别胶质瘤发生的驱动力
Metabolic dependencies and neural progenitor dysregulation: driving forces in paediatric high-grade glioma development.
儿童高级别胶质瘤(pHGGs)是儿童中最致命的脑肿瘤,其特征是深刻的表观遗传失调和有限的治疗选择。
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Metabolic dependencies and neural progenitor dysregulation: driving forces in paediatric high-grade glioma development.
儿童高级别胶质瘤(pHGGs)是儿童中最致命的脑肿瘤,其特征是深刻的表观遗传失调和有限的治疗选择。
Immunotherapy for pediatric solid tumors: overcoming biological barriers through rational multimodal combinations.
这些进展指向了一个未来,即针对儿童癌症独特免疫生物学定制的联合免疫治疗。
Immunotherapy-related neurotoxicity in the central nervous system of children with cancer.
我们对儿童患者免疫治疗相关神经毒性的理解仍存在显著空白,很大程度上是因为我们的知识大多来自成人研究。
Mesenchymal stem cell-based delivery systems for the treatment of brain tumors.
脑肿瘤属于最致命的癌症类型之列,在儿童和成人人群中均导致高死亡率。
Targeting oncometabolism to maximize immunotherapy in malignant brain tumors.
脑肿瘤在儿童和成人中均导致显著的发病率和死亡率。
Oncolytic Maraba Virus MG1 Mediates Direct and Natural Killer Cell-Dependent Lysis of Ewing Sarcoma.
MG1 能够直接杀死 EWS 细胞并刺激 NK 细胞对该肿瘤的细胞毒性,这表明 MG1 可能为常规治疗疗效目前有限的 EWS 患者提供治疗获益。
Tumor-Immune Interactions in Pediatric Oral Rhabdomyosarcoma: A Narrative Review on Immuno-Oncology and Emerging Therapies.
儿童口腔横纹肌肉瘤(RMS)是一种罕见且侵袭性强的头颈部肿瘤,其特征为复杂且以免疫抑制为主的肿瘤免疫微环境。
Epidemiology, Diagnostic Strategies, and Therapeutic Advances in Diffuse Midline Glioma.
目的:弥漫性中线胶质瘤(DMG)是一种高度侵袭性且致命的脑肿瘤,主要影响儿童和年轻成人。
Immunotherapy for the treatment of pediatric brain tumors: a narrative review.
本综述重点介绍了 20 篇已发表的文章,这些文章将免疫治疗用于儿童原发性脑肿瘤的治疗。
Oncolytic Maraba virus MG1 mediates direct and natural killer cell-dependent lysis of Ewing sarcoma.
30 多年来,尤因肉瘤的治疗进展相对有限。
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