细胞治疗时代大剂量 IL-2 在黑色素瘤中的作用
Role of high-dose interleukin-2 for melanoma in the age of cellular therapy.
白细胞介素-2(IL-2)是首批用于癌症患者治疗的免疫疗法之一。
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Role of high-dose interleukin-2 for melanoma in the age of cellular therapy.
白细胞介素-2(IL-2)是首批用于癌症患者治疗的免疫疗法之一。
Current landscape and future prospects of interleukin-2 receptor (IL-2R) agonists in cancer immunotherapy.
然而,不到50%的患者从ICB中获益,这凸显了对更有效免疫治疗选择的需求。
Generation and Characterization of Ex Vivo Expanded Tumor-infiltrating Lymphocytes From Renal Cell Carcinoma Tumors for Adoptive Cell Therapy.
自体治疗性TIL(肿瘤浸润淋巴细胞)疗法是一种增强抗肿瘤免疫的有前景的策略。
Immunologic Characterization and T cell Receptor Repertoires of Expanded Tumor-infiltrating Lymphocytes in Patients with Renal Cell Carcinoma.
在本研究中,我们根据临床级TIL生产方案,对未经治疗的肾细胞癌(RCC)患者的肿瘤样本(n = 58)、“快速扩增前”TIL(pre-REP TIL,n = 15)和“快速扩增”TIL(REP TIL,n = 25)进行了单细胞RNA(scRNA)+TCR测序(TCR sequencing)、TCR测序(TCR-seq)和流式细胞术分析。
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