CELL INTELLIGENCE · 肿瘤细胞治疗研究

IL-15 增强间皮素和 CD70 CAR NK 细胞在 PDAC 中的效力，双靶向未带来额外获益

IL-15 boosts mesothelin- and CD70-CAR NK cell potency in PDAC without added benefit from dual targeting.

将去甲基化药物与现货型 CD70 靶向嵌合抗原受体工程化自然杀伤 T 细胞协同用于治疗急性髓系白血病

Synergizing hypomethylating agents with off-the-shelf CD70-targeted chimeric antigen receptor-engineered natural killer T cells for the treatment of a

CD28 共刺激经 LCK/CD3ζ/ZAP70 信号轴增强 NK 细胞中的 CAR 信号传导

CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis.

蛋白酶体抑制增强表达嵌合抗原受体（CAR）的 NK 细胞对急性髓系白血病的抗白血病疗效

Proteasome inhibition enhances the anti-leukemic efficacy of chimeric antigen receptor (CAR) expressing NK cells against acute myeloid leukemia.

PIs 在体外和体内增强表达 CAR 的同种异体 NK 细胞对急性髓系白血病的抗白血病疗效，值得在早期临床试验中进一步探索这种联合治疗。

泌尿系统肿瘤中的 NK 细胞与 CAR-NK 细胞治疗：进展、来自 CAR-T 的机制启示及未来方向

Natural killer and CAR-NK cell therapies in urological cancers: Progress, mechanistic lessons from CAR-T, and future directions.

多发性骨髓瘤 CAR-NK 细胞治疗的最新进展：细胞来源与靶抗原的综合综述

State of the Art of CAR-NK Cell Therapy in Multiple Myeloma: A Comprehensive Review of Cell Sources and Target Antigens.

用于透明细胞肾细胞癌的嵌合抗原受体免疫细胞疗法：最新进展与方向

Chimeric Antigen Receptor-Immune Cell-Based Therapies for Clear Cell Renal Cell Carcinoma: Latest Advancements and Directions.

表达 IL-15 的 CD70 特异性 CAR NK 细胞治疗 CD19 阴性 B 细胞恶性肿瘤

CD70-specific CAR NK cells expressing IL-15 for the treatment of CD19-negative B-cell malignancy.

oHSV-1 感染的胶质母细胞瘤释放的 IFN-γ 增强 CD70 特异性 CAR-T 治疗

Enhancement of CD70-specific CAR T treatment by IFN-γ released from oHSV-1-infected glioblastoma.

靶向 CD70 的 CAR-T/NK 治疗：原理、进展和未来方向

CD70-targeted CAR-T/NK therapy: Rationale, advances, and future directions.