新型仿生纳米平台放大铁死亡以特异性激活 cGAS-STING 通路增强肝细胞癌化疗-免疫治疗
A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunothera
低免疫原性仍然是肝细胞癌(HCC)有效免疫治疗的关键障碍。
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A novel biomimetic nanoplatform amplifies ferroptosis for specific cGAS-STING pathway activation to enhance hepatocellular carcinoma chemo-immunothera
低免疫原性仍然是肝细胞癌(HCC)有效免疫治疗的关键障碍。
Therapeutic Potential of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Digestive System Tumors: Modulating the Chronic Inflammatory Microenv
消化系统肿瘤(包括结直肠癌、肝细胞癌和胃癌)已成为全球最严重的癌症负担之一,其病理演变与慢性炎症微环境密切相关。
Metabolic Dysfunction-associated Steatotic Liver Disease Diminishes the Efficacy of miR-125b-5p-engineered MSC Therapy for Hepatocellular Carcinoma vi
多基因修饰的 MSC 可实现有效的、经 MRI 监测的 HCC 治疗。
Astragaloside IV and rapamycin co-loaded bone marrow mesenchymal stem cell-derived exosome nanocarriers for targeted modulation of the PI3K/Akt/mTOR p
RAP@AST-IV/EXO NC 通过联合抑制 PI3K/Akt/mTOR 和诱导线粒体凋亡,代表了一种有前景且具有生物相容性的靶向 HCC 治疗策略。
In Vitro Analysis of PMEPA1 Upregulation in Mesenchymal Stem Cells Induced by Prostate Cancer Cells.
前列腺跨膜蛋白雄激素诱导1(PMEPA1)的不同亚型分别受TGF-beta或AR激活的调控,并对这些信号通路提供负反馈环路调节。
Roles of extracellular vesicles from different origins in metabolic-associated fatty liver disease: progress and perspectives.
代谢相关脂肪性肝病(MAFLD)是全球最常见的慢性肝病,与全身代谢紊乱相关。
c-MET and the immunological landscape of cancer: novel therapeutic strategies for enhanced anti-tumor immunity.
细胞间充质-上皮转化因子(c-MET),又称肝细胞生长因子受体(HGFR),是一种关键的受体酪氨酸激酶,与包括肺癌、乳腺癌和肝癌在内的多种实体瘤相关。
Human umbilical cord mesenchymal stem cell-derived exosomes ameliorate liver steatosis by promoting fatty acid oxidation and reducing fatty acid synth
MSC-ex可能通过CAMKK1介导的脂质稳态调节预防HFD诱导的NAFLD。
Identification of a CD4+ conventional T cells-related lncRNAs signature associated with hepatocellular carcinoma prognosis, therapy, and tumor microen
我们构建并验证了一种新的CD4+ Tconv相关lncRNAs RS,其具有预测HCC患者生存和免疫治疗反应的潜在价值。
Desialylated Mesenchymal Stem Cells-Derived Extracellular Vesicles Loaded with Doxorubicin for Targeted Inhibition of Hepatocellular Carcinoma.
本研究使用去唾液酸化MSC-EVs的递送系统的结果提示其用于HCC的治疗潜力。
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