CELL INTELLIGENCE · 肿瘤细胞治疗研究

泛素特异性蛋白酶 6 mRNA 脂质纳米颗粒在尤文肉瘤中激发抗肿瘤免疫并抑制肿瘤发生

Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma.

靶向 CD70 的 CAR-T/NK 治疗：原理、进展和未来方向

CD70-targeted CAR-T/NK therapy: Rationale, advances, and future directions.

叶酸受体-α CAR-T 细胞的临床前评价显示对骨肉瘤的高效抗肿瘤活性

Preclinical Evaluation of Folate Receptor-α Chimeric Antigen Receptor T Cells Exhibits Highly Efficient Antitumor Activity against Osteosarcoma.

进入场景：T(H)9 细胞向肺部优越的迁移能力解释了其卓越的抗癌疗效

Go to the scene: T(H)9 cells superior migration ability to the lungs explains their exceptional anticancer efficacy.

通过 IL-8 引导 B7-H3 CAR-T 细胞归巢诱导对儿童肉瘤的强效抗肿瘤活性

Directing B7-H3 chimeric antigen receptor T cell homing through IL-8 induces potent antitumor activity against pediatric sarcoma.

这些发现值得进一步研究 BC2 CAR-T 细胞用于治疗 RMS、OS 及其他表达 B7-H3、产生 IL-8 的实体瘤患者。

B7-H3 靶向 CAR-T 细胞在体外和体内对骨肉瘤表现出高效抗肿瘤功能

B7-H3 targeted CAR-T cells show highly efficient anti-tumor function against osteosarcoma both in vitro and in vivo.

我们的研究表明，靶向 B7-H3 的 CAR-T 细胞在体外和体内均对骨肉瘤具有较高的抗肿瘤疗效，这证明靶向 B7-H3 的 CAR-T 疗法对骨肉瘤治疗具有潜在疗效。