肿瘤细胞治疗研究
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The dual immunomodulatory role of B cells in tumorigenesis: mechanisms, microenvironment crosstalk, and therapeutic implications.
B 淋巴细胞在肿瘤生物学中展现出多面且依赖环境的作用，通过肿瘤微环境（TME）内的动态相互作用，既作为恶性肿瘤的促进者，也作为抑制者。
ITGAL expression in non-small-cell lung cancer tissue and its association with immune infiltrates.
ITGAL 可作为评估 NSCLC 患者免疫微环境的生物标志物。
Tumor microenvironment features decipher the outperformance of neoadjuvant immunochemotherapy over chemotherapy in resectable non-small cell lung canc
IO+化疗诱导的主要病理缓解（MPR）显著更高（75.0% vs.
Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome.
我们的结果提示，需要建立组织学亚型特异性的基于 TIL 的模型，用于生存风险分层和预测治疗应答。
Infiltration of NK and plasma cells is associated with a distinct immune subset in non-small cell lung cancer.
基于 RNA 测序数据，在 197 例患者中建立了转录组免疫模式。
POU2F2(+) B cells enhance antitumor immunity and predict better survival in non small cell lung cancer.
免疫检查点抑制剂是非小细胞肺癌（NSCLC）的有效辅助治疗。
Tumor microenvironment(TME) and single-source dual-energy CT(ssDECT) on assessment of inconformity between RECIST1.1 and pathological remission in neo
与化疗和靶向治疗相比，基于 RECIST 标准，新辅助免疫治疗的疗效因其独特的抗肿瘤治疗机制而被低估。术前 CD8+表达和 ssDECT 可预测这一 IC 并评估残留肿瘤细胞。这对于筛选免疫获益人群及更准确判断手术时机具有重要意义。
Spatial and temporal heterogeneity of tumor immune microenvironment between primary tumor and brain metastases in NSCLC.
NCSLC 的原发肿瘤与脑转移灶之间存在时间和空间异质性。脑转移病灶表现出更强的免疫抑制性肿瘤免疫微环境。B7-H4 和 CD68+ TAMs 可能对肺腺癌脑转移患者具有潜在治疗价值。
FoxP3 Expression in Tumor-Infiltrating Lymphocytes as Potential Predictor of Response to Immune Checkpoint Inhibitors in Patients with Advanced Melano
我们评估了 46 例接受 ICI 单药治疗的晚期 MM（31 例）和 NSCLC（15 例）患者。
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