胃肠道肿瘤:分子发病机制与靶向治疗
Gastrointestinal cancer: molecular pathogenesis and targeted therapy.
胃肠道(GI)癌症构成了重大的全球健康负担,其驱动因素是复杂的分子改变和微环境相互作用。
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Gastrointestinal cancer: molecular pathogenesis and targeted therapy.
胃肠道(GI)癌症构成了重大的全球健康负担,其驱动因素是复杂的分子改变和微环境相互作用。
Dynamic Changes in Circulating and Tissue Biomarkers and Therapeutic Response to HER2/PD-1 Dual Blockade in HER2-Positive Gastric Cancer.
整合ctDNA和免疫生物标志物监测可能为双重HER2/PD-1阻断治疗提供预后信息。连续分子谱分析能够实现早期耐药检测,并识别可能指导治疗策略的进化模式,但仍需前瞻性验证。
Targeted therapy and immunotherapy for gastric cancer: rational strategies, novel advancements, challenges, and future perspectives.
胃癌(GC)是全球最常见的恶性肿瘤之一,其治疗一直是医学研究的重点。
Characteristics of the immunogenicity and tumor immune microenvironment in HER2-amplified lung adenocarcinoma.
HER2扩增的LUAD患者在HER2异常肿瘤中具有更好的免疫原性和/或炎症性TIME。我们的研究可能为确立ICIs对该疾病患者的获益和应用提供线索。
Analysis of clinicopathological and molecular characteristics of EBV-associated gastric cancer.
EBV-GC具有独特的临床病理和分子特征。病理检查、免疫分型和NGS对诊断和治疗方向具有重要价值。
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