用异体恒定自然杀伤 T 细胞(iNKT)克服程序性细胞死亡蛋白 1(PD-1)阻断的耐药性
Overcoming resistance to programmed cell death protein 1 (PD-1) blockade with allogeneic invariant natural killer T-cells (iNKT).
胃癌是全球第5大常见恶性肿瘤,转移性疾病患者中仅有36%生存超过5年。
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Overcoming resistance to programmed cell death protein 1 (PD-1) blockade with allogeneic invariant natural killer T-cells (iNKT).
胃癌是全球第5大常见恶性肿瘤,转移性疾病患者中仅有36%生存超过5年。
IL-17A functions and the therapeutic use of IL-17A and IL-17RA targeted antibodies for cancer treatment.
白细胞介素17A(IL-17A)是IL-17细胞因子家族的主要成员,主要由辅助性T细胞17(Th17)产生。
A combined analysis of bulk and single-cell sequencing data reveals that depleted extracellular matrix and enhanced immune processes co-contribute to
氟尿嘧啶,也称为5-FU,是治疗晚期胃癌(GC)最常用的化疗药物之一。
First-in-Human Phase 1 Study of a B Cell- and Monocyte-Based Immunotherapeutic Vaccine against HER2-Positive Advanced Gastric Cancer.
BVAC-B 单药治疗具有安全的毒性特征,但临床活性有限;然而,它在经过大量预治疗的 HER2 阳性胃癌患者中激活了免疫细胞。有必要在更早期治疗中采用 BVAC-B 及联合治疗以评估临床疗效。
CD4(-)/CD8(-) double-negative tumor-infiltrating lymphocytes expanded from solid tumor tissue suppress the proliferation of tumor cells in an MHC-inde
胃癌来源的DN-TIL能够在体外和体内靶向肿瘤细胞。DN-TIL有潜力作为实体癌的过继细胞疗法,兼具DNT和TIL的优势。
Unravelling diagnostic clusters and immune landscapes of disulfidptosis patterns in gastric cancer through bioinformatic assay.
二硫死亡是一种由SLC7A11诱导的二硫化物应激介导的新型细胞死亡方式。
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