CELL INTELLIGENCE · 肿瘤细胞治疗研究

从受体生物学到治疗：不同 EGFR 突变在靶向癌症治疗开发中的重要性

From receptor biology to therapy: importance of different EGFR mutations in the development of targeted cancer therapies.

局部晚期头颈部鳞状细胞癌免疫治疗-放疗/化疗联合方案中的耐药机制

Resistance Mechanisms in Immunotherapy-Radiotherapy/Chemotherapy Combinations in Locally Advanced Head & Neck Squamous Cell Carcinoma.

EGFR/HER2 双靶点 CAR-NK 细胞治疗复发或转移性头颈部鳞状细胞癌

EGFR/HER2 Dual-Target CAR-NK Cells for Recurrent or Metastatic HNSCC

这是一项 I/II 期、非随机的注册临床试验，评估 HER2NK 细胞治疗头颈部鳞癌的疗效与安全性。研究设计：非随机。当前状态：招募中。计划入组 42 例。试验地点：中国 · 深圳（共 1 个中心，其中中国 1 个）。登记号：NCT07617805。

靶向头颈部鳞状细胞癌中的 NKG2D 轴：从分子机制到临床应用

Targeting the NKG2D axis in head and neck squamous cell carcinoma: from molecular insights to clinical applications.

双重二酰甘油激酶（DGK）α/ζ 抑制剂在体内和离体模型中增强人 TIL（肿瘤浸润淋巴细胞）的活性

A dual diacylglycerol kinase (DGK) alpha/zeta inhibitor augments the activity of human tumor infiltrating lymphocytes in in vivo and ex vivo models.

头颈癌中临床相关基因融合的患病率及生物学影响

Prevalence and biological impact of clinically relevant gene fusions in head and neck cancers.

头颈部鳞状细胞癌 CAR-T 细胞治疗的进展与挑战

Advances and challenges in CAR-T cell therapy for head and neck squamous cell carcinoma.

EpCAM 信号通路在口腔癌干细胞中的作用：对转移、致瘤性及治疗策略的意义

EpCAM Signaling in Oral Cancer Stem Cells: Implications for Metastasis, Tumorigenicity, and Therapeutic Strategies.

探索 CAR-NK 细胞治疗在头颈部癌（HNC）管理中的潜力：叙述性综述

Exploring the potential of CAR-NK cell therapy in the management of head and neck cancer (HNC): a narrative review.

CAR-NK 细胞通过将靶向细胞毒作用与更优的安全性特征相结合，为 HNSCC 提供了新的治疗途径。

头颈癌的免疫治疗

Immunotherapy in Head and Neck Cancer.