Stemsome 表面蛋白质组重编程通过增强的受体-配体相互作用促进肺癌靶向
Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor-Ligand Interactions.
肿瘤细胞治疗研究
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把在研试验和前沿论文合在一起看,按时间倒序排列。本页条数 = 前沿论文 + 临床试验两块之和(导航里的「临床试验」板块只收在招的那部分,不另计入)。
Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor-Ligand Interactions.
Click Chemistry Mediated Immune Synapse Augmentation in Natural Killer Cell-Cancer Membrane Engagement and Facilitated Anticancer Efficacies of Natura
Dual Roles of hABCB1 in Drug Resistance and Immune Evasion: Implications for Lung Cancer Therapy.
Dendritic Cell Immunotherapy for Solid Tumors: Advances in Translational Research and Clinical Application.
Advances in Non-Small Cell Lung Cancer Cellular Immunotherapy: A Progress in Dendritic Cell, T-Cell, and NK Cell Vaccines.
Fucoidan from Durvillaea Antarctica elicits anticancer immunity against lung cancer via natural killer cell activation.
Effects of Bojungikki-Tang on immune response and clinical outcomes in NSCLC patients receiving immune checkpoint inhibitors: a randomized pilot study
BJIKT 可能增强接受免疫检查点抑制剂治疗的 NSCLC 患者的免疫应答,并可能改善临床结局;然而,这些探索性且大多无统计学显著性的发现需要谨慎解读,并在更大规模的试验中进一步验证。试验注册:该试验于 2021 年 10 月在 Clinical Research Information Service(https://cris.nih.go.kr/cris;注册号:KCT0006689)注册。
Single-cell RNA sequencing of baseline PBMCs predicts ICI efficacy and irAE severity in patients with NSCLC.
本研究通过治疗前的 PBMC 样本,识别了与 ICI 预后和 irAE 严重程度相关的生物学通路及关键生物标志物。这些发现为改进治疗策略奠定了基础,从而在提高临床疗效的同时最大限度降低 ICI 治疗相关风险。
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