接受 BiTEs 和 CAR-T 细胞治疗的多发性骨髓瘤感染风险的真实世界证据:一项荟萃分析
Real-world evidence on infection risk in multiple myeloma treated with BiTEs and CAR-T cells: a meta-analysis.
在真实世界实践中,接受 T 细胞重定向治疗的 RRMM 患者中约每 4 例就有 1 例发生严重感染。
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Real-world evidence on infection risk in multiple myeloma treated with BiTEs and CAR-T cells: a meta-analysis.
在真实世界实践中,接受 T 细胞重定向治疗的 RRMM 患者中约每 4 例就有 1 例发生严重感染。
Dual-antigen-targeting T-cell immunotherapies in MM: circumventing tumor heterogeneity and preventing antigen escape.
双靶向最终应在大规模 III 期试验中,与靶点转换的单靶向药物序贯治疗这一经典方案进行比较。
T-cell dynamics, CD8/NK ratio and tumor survival hallmarks determine response to T-cell bispecific forimtamig in myeloma.
这些挑战要求我们采用新方法来优化治疗,并最终理解耐药机制。
Natural Taste Modulators and Microbiome-Aware Nutritional Support for Immunotherapy-Associated Dysgeusia: A Translational Perspective for Precision Su
味觉障碍是癌症治疗中一种具有临床后果但仍缺乏标准化的毒性反应。
Sequencing BCMA- and GPRC5D-targeting immunotherapies in multiple myeloma: Practical guidance from the European Myeloma Network.
近年来,随着针对BCMA和GPRC5D的新型免疫疗法的引入,包括CAR T细胞疗法、双特异性抗体(BsAbs)和抗体-药物偶联物,经过多线治疗的复发/难治性MM的治疗格局已发生显著变化。
Novel immunotargets in multiple myeloma: biological relevance and therapeutic potential.
多发性骨髓瘤是一种血液系统恶性肿瘤,其特征是复杂的遗传和微环境因素驱动疾病进展和治疗耐药。
Experiences and expert panel consensus on bridging therapy before anti-BCMA CAR-T cell therapy in multiple myeloma.
使用抗 B 细胞成熟抗原(BCMA)CAR-T 细胞疗法治疗复发/难治性多发性骨髓瘤的情况正在增加。
Sequential CAR T-cell therapy in myeloma: going from BCMA to GPRC5D.
Multiomic profiling of T cell lymphoma after therapy with anti-BCMA CAR T cells and GPRC5D-directed bispecific antibody.
嵌合抗原受体(CAR)T细胞和双特异性T细胞衔接器已成为复发/难治性多发性骨髓瘤治疗中不可或缺的组成部分。
Navigating the Post-BCMA/GPRC5D Landscape: Efficacy of Selinexor, Bortezomib, and Dexamethasone After Sequential Immunotherapy Failure in Penta-Refrac
总体缓解率(ORR)为61%,包括1例完全缓解、5例非常好的部分缓解和5例部分缓解,中位无进展生存期(PFS)为4.3个月。
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