CELL INTELLIGENCE · 肿瘤细胞治疗研究

从临床样本中优化获取抗癌反应性 T 细胞受体

Optimized procurement of cancer-reactive T-cell receptors from clinical samples.

效应 Vδ1 γδ T 细胞介导抗肿瘤免疫并在人胃肠道间质瘤中被伊马替尼重编程

Effector Vδ1 γδ T cells mediate anti-tumor immunity and are reprogrammed by imatinib in human gastrointestinal stromal tumor.

GD2 异体 T 细胞治疗神经母细胞瘤、骨肉瘤：I 期临床试验（Emory）

Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma

这是一项 I 期注册临床试验，评估异体 T 细胞治疗神经母细胞瘤、骨肉瘤的疗效与安全性。当前状态：招募中。计划入组 24 例。试验地点：美国 · 亚特兰大（共 1 个中心）。登记号：NCT05400603。

AI 辅助的外周免疫分析揭示了与软组织肉瘤患者预后相关的非常规淋巴细胞特征

AI-assisted peripheral immune profiling reveals unconventional lymphocyte signatures associated with prognosis in soft tissue sarcoma patients.

通过 TGF-β扩增获得的中央记忆富集 Vγ9Vδ2 γδ T 细胞在体内对转移性骨肉瘤显示出增强的疗效

Central memory-enriched Vγ9Vδ2 γδ T cells via TGF-β expansion demonstrate enhanced in vivo efficacy against metastatic osteosarcoma.

鉴定一种促蛋白合成型骨肉瘤亚型用于预测预后和治疗

Identification of a pro-protein synthesis osteosarcoma subtype for predicting prognosis and treatment.

骨肉瘤医学顾问委员会智库会议纪要

Proceedings of the Think Tank for Osteosarcoma Medical Advisory Board.

递送载荷的工程化γδ T 细胞在骨肉瘤临床前模型中显示出增强的细胞毒性、持久性和疗效

Payload-delivering engineered γδ T cells display enhanced cytotoxicity, persistence, and efficacy in preclinical models of osteosarcoma.

RAMP1 作为泛癌和骨肉瘤中的新型预后生物标志物

RAMP1 as a novel prognostic biomarker in pan-cancer and osteosarcoma.

基底细胞癌（BCC）肿瘤微环境与其他实体恶性肿瘤的比较

Comparison of the Basal Cell Carcinoma (BCC) Tumour Microenvironment to Other Solid Malignancies.