CELL INTELLIGENCE · 肿瘤细胞治疗研究

胃癌腹膜转移中的肿瘤相关巨噬细胞：协调免疫逃逸、微环境重塑和治疗耐药

Tumor-associated macrophages in gastric cancer peritoneal metastasis: orchestrating immune evasion, niche remodeling, and therapeutic resistance.

FDX1 表达促进 DSF/Cu 诱导的胃癌细胞铜死亡

FDX1 expression promotes DSF/Cu-induced cuproptosis in gastric cancer cells.

本研究表明，DSF/Cu 促进铜死亡，FDX1 的表达影响 GC 对铜死亡的敏感性。此外，NK 细胞外泌体与 DSF/Cu 联合应用提高了 DSF/Cu 的治疗效果，有助于推动 GC 的靶向治疗并提高临床适用性。

胃癌中的糖酵解驱动免疫抑制：肿瘤细胞与免疫微环境之间的代谢串扰（综述）

Glycolysis‑driven immunosuppression in gastric cancer: Metabolic crosstalk between tumor cells and the immune microenvironment (Review).

胃癌细胞来源外泌体 circPDSS1 通过调控 miR-142-3p/ACSL4 分子轴促进 NK 细胞铁死亡

Exosomal circPDSS1 Derived From Gastric Cancer Cells Promotes Natural Killer Cell Ferroptosis by Regulating the miR-142-3p/ACSL4 Molecular Axis.

间充质干细胞来源细胞外囊泡在消化系统肿瘤中的治疗潜力：调控慢性炎症微环境

Therapeutic Potential of Mesenchymal Stem Cell-Derived Extracellular Vesicles in Digestive System Tumors: Modulating the Chronic Inflammatory Microenv

通过 IL4R 外泌体阻断 APP-CD74 调控肿瘤相关巨噬细胞与 PD-1 抑制在胃癌中协同作用

Modulating tumor-associated macrophages through APP-CD74 blockade with IL4R-exosomes synergizes with PD-1 inhibition in gastric cancer.

携带 CLDN4 靶向肽的 NK 细胞来源小细胞外囊泡增强胃癌放疗效果

NK Cell-Derived Small Extracellular Vesicles Armed With CLDN4-Targeting Peptides Potentiate Radiotherapy in Gastric Cancer.

细胞外囊泡来源的 lncRNA-GC1 可作为预测和监测胃癌患者免疫治疗结局的新型生物标志物

Extracellular vesicle-derived lncRNA-GC1 serves as a novel biomarker for predicting and monitoring the immunotherapeutic outcomes of patients with gas

EV 衍生的 lncRNA-GC1 可用于可靠预测接受 ICI 治疗的 GC 患者的免疫治疗结局，提示对该 lncRNA 进行靶向分析可能有助于指导治疗计划、监测及相关决策过程。

间充质干细胞来源外泌体对主要实体恶性肿瘤的治疗潜力：一项叙述性系统综述

Therapeutic potentials of mesenchymal stem cell-derived exosomes for major solid malignancies: A narrative systematic review.

利用外泌体：从肿瘤免疫逃逸到胃癌免疫治疗中的治疗创新

Harnessing exosomes: From tumor immune escape to therapeutic innovation in gastric cancer immunotherapy.