面向实体瘤的工程化 CAR-T 细胞:通过整合设计与临床转化克服微环境
Engineering CAR-T cells for solid tumors: Overcoming the microenvironment through integrated design and clinical translation.
CAR-T 细胞疗法在血液肿瘤中已取得显著的治疗效果,而其应用于实体恶性肿瘤仍受限于约9%的汇总客观缓解率。
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FRONTIER PAPERS
Engineering CAR-T cells for solid tumors: Overcoming the microenvironment through integrated design and clinical translation.
CAR-T 细胞疗法在血液肿瘤中已取得显著的治疗效果,而其应用于实体恶性肿瘤仍受限于约9%的汇总客观缓解率。
Chimeric Antigen Receptor T cell Therapy and the Immunosuppressive Tumor Microenvironment in Pediatric Sarcoma.
肉瘤是一组多样化的骨和软组织肿瘤,占儿童癌症的10%以上。
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