肿瘤细胞治疗研究
FRONTIER PAPERS
Injectable Hydrogels for Breast Cancer Therapy: From Tumor Microenvironment-Responsive and Actively Targeted Drug Delivery to Immunotherapy and Theran
乳腺癌治疗仍面临诸多挑战，包括局部复发、全身毒性、肿瘤异质性、耐药和免疫抑制。
Chimeric antigen receptor NK cells for breast cancer immunotherapy.
乳腺癌是全球女性中最常见的恶性肿瘤，需要超越手术、化疗、放疗和内分泌治疗等传统疗法的创新治疗策略。
Preclinical efficacy of a HER2 synNotch/CEA-CAR combinatorial immunotherapy against colorectal cancer with HER2 amplification.
HER2 扩增见于约 5% 的结直肠癌（CRC）病例，且仅部分与联合人表皮生长因子受体 2（HER2）/表皮生长因子受体（EGFR）靶向治疗的临床应答相关。
Locoregional and systemic adoptive cellular therapies for pediatric brain tumors: a systematic review of CAR‑T, TCR‑engineered T cells, and NK cell st
检索获得 324 条记录；去除 103 条重复记录；筛选 221 篇标题和摘要；审阅 180 篇全文；由两名独立评价者提取 34 项研究。
Evaluation of Efficacy and Safety of Chimeric Antigen Receptor-Natural Killer (CAR-NK) Cells in Breast Cancer: A Systematic Review and Meta-Analysis.
在汇总的临床前分析中，CAR-NK 相较于未处理对照和未修饰/模拟对照显著降低了肿瘤负荷（ROM 分别为 0.311 [0.22-0.44] 和 0.42 [0.33-0.53]，p < 0.001）。
Prospective Molecular Targets for Natural Killer Cell Immunotherapy against Glioblastoma Multiforme.
多形性胶质母细胞瘤（GBM）是最常见的原发性恶性脑肿瘤类型，总生存率极低。
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