CELL INTELLIGENCE · 肿瘤细胞治疗研究

诊断时 CD70 过表达预测滤泡性淋巴瘤复发并支持 CD19-CD70 双靶点 CAR-T 治疗

CD70 Overexpression at Diagnosis Predicts Relapse and supports dual CD19-CD70 CAR-T Therapy in Follicular Lymphoma.

寻找 AML 中安全有效的 CAR-T 靶点

The search for safe and effective CAR-T targets in AML.

血液学之外——嵌合抗原受体（CAR）T 细胞治疗皮肤与结缔组织疾病的最新认识

Beyond Hematology-Current Insights into Chimeric Antigen Receptor (CAR) T-Cell Therapy for Skin and Connective Tissue Disorders.

急性髓系白血病 CAR-T 细胞治疗的新兴策略：通过双抗原靶向克服异质性并提高安全性

Emerging strategies in CAR-T cell therapy for acute myeloid leukemia: overcoming heterogeneity and improving safety through dual-antigen targeting.

靶向 CD70 的癌症诊疗一体化：进展与挑战

CD70-targeted cancer theranostics: Progress and challenges.

敲除 CD70 使 CD70 特异性 NanoCAR T 细胞免于抗原诱导的耗竭

Knocking Out CD70 Rescues CD70-Specific NanoCAR T Cells from Antigen-Induced Exhaustion.

靶向泛癌靶点 CD70 的分泌 IL-15 的 CAR NK 细胞同时清除癌细胞与癌相关成纤维细胞

IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.

我们揭示 CD70 在血液肿瘤和实体瘤中均是一个有吸引力的靶点。经 IL-15 武装的 CAR NK 细胞可作为强效效应细胞清除这些 CD70+细胞。它们可靶向 CRC 和 PDAC 患者的肿瘤细胞和 CAFs，并可能靶向其他促结缔组织增生性实体瘤。

结外鼻型 NK/T 细胞淋巴瘤中可溶性 CD27 的表达：作为诊断和 CD27/CD70 靶向治疗生物标志物的潜力

Expression of soluble CD27 in extranodal natural killer/T-cell lymphoma, nasal type: potential as a biomarker for diagnosis and CD27/CD70-targeted the

通过溶瘤病毒基因治疗同时靶向 CD40/4-1BB 以增强淋巴瘤中 CAR-T 细胞应答

Boosting CAR T-cell responses in lymphoma by simultaneous targeting of CD40/4-1BB using oncolytic viral gene therapy.