CAR-T 细胞:改善儿童肿瘤结局所缺失的一环?
CAR T cells: the missing piece needed to improve outcomes for children with cancer?
B 细胞急性淋巴细胞白血病 (B-ALL) 是儿童期最常见的癌症。
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CAR T cells: the missing piece needed to improve outcomes for children with cancer?
B 细胞急性淋巴细胞白血病 (B-ALL) 是儿童期最常见的癌症。
T cells expressing CD5/CD7 bispecific chimeric antigen receptors with fully human heavy-chain-only domains mitigate tumor antigen escape.
双特异性 CAR-T 细胞疗法在晚期 B 细胞恶性肿瘤的临床试验中显示出有希望的结果。
Contemporary management of diffuse large B-cell lymphoma in Japan.
由专家或通过会诊网络对 DLBCL 进行准确的病理诊断至关重要,而一种新兴的基因组检测将有助于未来的精准诊疗方法。
BL-01, an Fc-bearing, tetravalent CD20 × CD5 bispecific antibody, redirects multiple immune cells to kill tumors in vitro and in vivo.
作者认为,bsAb 在体内的疗效归因于 Fc 对先天免疫的联合激活以及将 CIK 细胞重定向以杀伤肿瘤靶标。
The effective and safe administration of Epcoritamab in relapsed CD19-CD5+ DLBCL following CAR-T therapy.
该病例凸显了 epcoritamab 联合减瘤治疗用于治疗 CAR-T 难治性 CD19 阴性 DLBCL 的潜力。
Nanobody-derived bispecific CAR-T cell therapy enhances the anti-tumor efficacy of T cell lymphoma treatment.
T 细胞淋巴瘤(TCL)是一组高度异质性的疾病,预后差,5 年总生存率低。
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