CELL INTELLIGENCE · 肿瘤细胞治疗研究

B 细胞在肿瘤发生中的双重免疫调节作用：机制、微环境串扰与治疗意义

The dual immunomodulatory role of B cells in tumorigenesis: mechanisms, microenvironment crosstalk, and therapeutic implications.

ITGAL 在非小细胞肺癌组织中的表达及其与免疫浸润的关联

ITGAL expression in non-small-cell lung cancer tissue and its association with immune infiltrates.

ITGAL 可作为评估 NSCLC 患者免疫微环境的生物标志物。

肿瘤微环境特征揭示了新辅助免疫化疗在可切除非小细胞肺癌中优于化疗的原因

Tumor microenvironment features decipher the outperformance of neoadjuvant immunochemotherapy over chemotherapy in resectable non-small cell lung canc

图像分析揭示 NSCLC 中与治疗结局相关的 TIL 分子差异模式

Image analysis reveals molecularly distinct patterns of TILs in NSCLC associated with treatment outcome.

NK 细胞和浆细胞的浸润与非小细胞肺癌中一个独特的免疫亚群相关

Infiltration of NK and plasma cells is associated with a distinct immune subset in non-small cell lung cancer.

POU2F2(+) B 细胞增强抗肿瘤免疫并预测非小细胞肺癌患者更好的生存

POU2F2(+) B cells enhance antitumor immunity and predict better survival in non small cell lung cancer.

肿瘤微环境（TME）与单源双能量 CT（ssDECT）在评估 NSCLC 新辅助免疫治疗中 RECIST1.1 与病理缓解不一致性方面的作用

Tumor microenvironment(TME) and single-source dual-energy CT(ssDECT) on assessment of inconformity between RECIST1.1 and pathological remission in neo

与化疗和靶向治疗相比，基于 RECIST 标准，新辅助免疫治疗的疗效因其独特的抗肿瘤治疗机制而被低估。术前 CD8+表达和 ssDECT 可预测这一 IC 并评估残留肿瘤细胞。这对于筛选免疫获益人群及更准确判断手术时机具有重要意义。

NSCLC 原发肿瘤与脑转移瘤之间肿瘤免疫微环境的空间和时间异质性

Spatial and temporal heterogeneity of tumor immune microenvironment between primary tumor and brain metastases in NSCLC.

NCSLC 的原发肿瘤与脑转移灶之间存在时间和空间异质性。脑转移病灶表现出更强的免疫抑制性肿瘤免疫微环境。B7-H4 和 CD68+ TAMs 可能对肺腺癌脑转移患者具有潜在治疗价值。

TIL（肿瘤浸润淋巴细胞）中 FoxP3 表达作为晚期黑色素瘤和非小细胞肺癌患者免疫检查点抑制剂治疗反应的潜在预测指标

FoxP3 Expression in Tumor-Infiltrating Lymphocytes as Potential Predictor of Response to Immune Checkpoint Inhibitors in Patients with Advanced Melano