CELL INTELLIGENCE · 肿瘤细胞治疗研究

靶向 CD79b 的三种新型 CAR 用于非霍奇金淋巴瘤治疗的临床前开发及靶抗原丢失特征分析

Preclinical development of three novel CARs targeting CD79b for the treatment of non-Hodgkin's lymphoma and characterization of the loss of the target

基于特异性、疗效和靶抗原丢失，CARLY3 代表了一种针对非霍奇金淋巴瘤的潜在新型 CAR 治疗。

NKTR-255 联合 CD19-22 CAR-T 细胞疗法治疗难治性 B 细胞急性淋巴细胞白血病的 1 期临床试验

A phase 1 clinical trial of NKTR-255 with CD19-22 CAR T-cell therapy for refractory B-cell acute lymphoblastic leukemia.

靶向 CD19/20 的双特异性 CAR-T 细胞治疗复发/难治性 B 细胞非霍奇金淋巴瘤患者：一项 I/II 期试验

Bispecific CAR-T cells targeting CD19/20 in patients with relapsed or refractory B cell non-Hodgkin lymphoma: a phase I/II trial.

双靶向 CD19 和 CD22 的 CAR-T 细胞治疗儿童和年轻成人复发/难治性 B 细胞急性淋巴细胞白血病：一项 1 期试验

CAR T cells with dual targeting of CD19 and CD22 in pediatric and young adult patients with relapsed or refractory B cell acute lymphoblastic leukemia