抗 BCMA CAR-T 细胞与靶向 GPRC5D 双特异性抗体治疗后的 T 细胞淋巴瘤多组学分析
Multiomic profiling of T cell lymphoma after therapy with anti-BCMA CAR T cells and GPRC5D-directed bispecific antibody.
嵌合抗原受体(CAR)T细胞和双特异性T细胞衔接器已成为复发/难治性多发性骨髓瘤治疗中不可或缺的组成部分。
FRONTIER PAPERS
Multiomic profiling of T cell lymphoma after therapy with anti-BCMA CAR T cells and GPRC5D-directed bispecific antibody.
嵌合抗原受体(CAR)T细胞和双特异性T细胞衔接器已成为复发/难治性多发性骨髓瘤治疗中不可或缺的组成部分。
Cutaneous Toxicities of T-Cell-Redirecting Therapies in Multiple Myeloma: An EADV Task Force Position Paper and Practical Recommendations.
T细胞重定向免疫疗法,包括双特异性抗体和嵌合抗原受体(CAR)T细胞疗法,已迅速成为复发或难治性多发性骨髓瘤的主要治疗选择,但与一系列独特的皮肤毒性相关。
Real-World Evidence of Immunotherapy Sequencing in Multiple Myeloma: Durable Responses With BCMA-Targeting Bispecific Antibodies Following Prior GPRC5
靶向BCMA的双特异性抗体为经靶向GPRC5D的双特异性抗体治疗后进展的患者提供了一种有效且耐受性良好的治疗选择,支持该序贯方案作为一种有前景策略的可行性。
Anti-BCMA and GPRC5D bispecific antibodies in relapsed/refractory primary plasma cell leukemia: a case report.
浆细胞白血病(PCL)是多发性骨髓瘤(MM)的一种侵袭性高危变异型,预后极差。
SOHO State of the Art Updates and Next Questions | Treatment of Myeloma Early Relapse: Non-CAR T Cell.
早期复发多发性骨髓瘤的治疗应个体化,以优化患者结局,并在可接受的毒性特征下实现长期缓解。
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