仅仅是触及表面:靶向细胞膜蛋白的多发性骨髓瘤新型治疗方法
Just scratching the surface: novel treatment approaches for multiple myeloma targeting cell membrane proteins.
对适应性免疫系统和固有免疫系统在包括多发性骨髓瘤(MM)在内的癌症发生中所起作用有了更深入的了解,这促进了新型免疫疗法的开发。
FRONTIER PAPERS
Just scratching the surface: novel treatment approaches for multiple myeloma targeting cell membrane proteins.
对适应性免疫系统和固有免疫系统在包括多发性骨髓瘤(MM)在内的癌症发生中所起作用有了更深入的了解,这促进了新型免疫疗法的开发。
Poor outcomes with BCMA-targeting bispecific antibodies following early relapse from ide-cel: a real-world French study.
抗BCMA BsAb疗效有限,而非BCMA BsAb可能在ide-cel早期复发后提供一种有前景的治疗方法。
Patient selection for CAR T or BiTE therapy in multiple myeloma: Which treatment for each patient?
多发性骨髓瘤(MM)是一种浆细胞恶性肿瘤,全球受累患者数量不断增加。
Bispecific antibodies in multiple myeloma: maximizing potential through rational combination therapies.
双特异性抗体已成为多发性骨髓瘤(MM)中一种变革性免疫治疗策略。
Beyond the marrow: insights from comprehensive next-generation sequencing of extramedullary multiple myeloma tumors.
本研究是迄今为止对EMM肿瘤(N = 14)最全面的下一代测序分析,揭示了关键分子特征并描述了肿瘤微环境。
The evolution of bispecific antibodies in multiple myeloma.
多发性骨髓瘤(MM)的治疗在过去十年中发生了革命性变化,随着靶向CD38的单克隆抗体如达雷妥尤单抗和伊沙妥昔单抗的问世,这些药物已被整合到新诊断或复发和/或难治性(R/R)MM患者的治疗武器库中。
Are we there yet? CAR-T therapy in multiple myeloma.
过去几年,随着新型抗原靶点的出现,针对多发性骨髓瘤(MM)的细胞免疫治疗发生了革命性变化。
Bispecific antibodies for the treatment of relapsed/refractory multiple myeloma: updates and future perspectives.
对五种最有效的抗MM药物均难治的复发/难治性多发性骨髓瘤(RRMM)患者,即所谓五药难治性MM,其后续治疗历来预后极差。
T-cell redirecting bispecific and trispecific antibodies in multiple myeloma beyond BCMA.
靶向替代性肿瘤相关抗原的新型T细胞重定向BsAb在重度经治MM中显示出巨大前景,包括既往接受过BCMA靶向治疗的患者。
Promising Antigens for the New Frontier of Targeted Immunotherapy in Multiple Myeloma.
近年来多发性骨髓瘤(MM)治疗中新型药物的纳入改善了患者的临床结局。
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