一种预测肿瘤内 CD8(+) T 细胞扩增的泛免疫治疗特征
A pan-immunotherapy signature to predict intratumoral CD8(+) T cell expansions.
FRONTIER PAPERS
A pan-immunotherapy signature to predict intratumoral CD8(+) T cell expansions.
NR4A ablation improves mitochondrial fitness for long persistence in human CAR-T cells against solid tumors.
NR4A 因子通过线粒体基因表达调控 CAR-T 细胞的持久性和干性,因此 NR4A 是生成针对实体瘤的优质 CAR-T 细胞的高度有前景的靶点。
Combined genomic and molecular analysis defines prognostic markers of relapse in stage IA-IC1 clear cell ovarian carcinoma.
ARID1A 野生型状态与低 CD3⁺ TIL 水平的组合提示低分期 CCOC 的复发风险较高。
NK Cells Can Target Castration-resistant Prostate Cancer Stem Cells With the Involvement of Degranulation Pathway.
这些观察结果提示,利用 NK 细胞靶向 CRPC 干细胞可能有助于建立抑制 CRPC 发展的新型治疗策略。
The activities and regulatory landscape of cellular therapies including hematopoietic cell transplantation in the world.
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