Durvalumab 和 tremelimumab 用于晚期罕见癌症患者:一项多中心、非盲、开放标签 II 期篮式试验
Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trial.
度伐利尤单抗+替西木单抗治疗在唾液腺癌和CCCO中产生了有意义的缓解,值得在一线研究中进一步探索。
FRONTIER PAPERS
Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trial.
度伐利尤单抗+替西木单抗治疗在唾液腺癌和CCCO中产生了有意义的缓解,值得在一线研究中进一步探索。
Chemotherapy, immunotherapy, and targeted therapy for osteosarcoma: Recent advancements.
骨肉瘤是一种罕见且侵袭性强的骨癌,其治疗的最新进展体现为化疗、免疫治疗和靶向治疗取得的显著进步。
Overall review of curative impact and barriers of CAR-T cells in osteosarcoma.
骨肉瘤(OS)是一种罕见的癌症,也是儿童和青少年中的原发性骨恶性肿瘤。
Prospects and Advances in Adoptive Natural Killer Cell Therapy for Unmet Therapeutic Needs in Pediatric Bone Sarcomas.
恶性骨肿瘤是具有高度转移倾向的侵袭性肿瘤,最常见于处于快速生长突增期的青少年。
The therapeutic potential of exosomes in bone cancers: osteosarcoma, chondrosarcoma, and Ewing sarcoma.
骨肉瘤(OS)、软骨肉瘤(CHS)和尤文肉瘤(EwS)是最常见的原发性骨癌(BCs)。
Digging Through the Complexities of Immunological Approaches in Emerging Osteosarcoma Therapeutics: A Comprehensive Narrative Review with Updated Clin
手术与新辅助化疗及术后化疗的结合,已使局限性OS肿瘤患者的5年生存率显著提高至70%以上。
Initial insights into the interaction of antibodies radiolabeled with Lutetium-177 and Actinium-225 with tumor microenvironment in experimental human
IHC显示,经225 Ac-和177 Lu标记的IF3抗体治疗后,IGF2R阳性OS细胞和OS干细胞群体减少。值得注意的是,放射性标记的IF3抗体有效减少了促肿瘤M2巨噬细胞,突显了其治疗前景。该研究还揭示了自然杀伤(NK)细胞和M1巨噬细胞的多样反应,阐明了TME中复杂的相互作用。在RIT后24和72小时,用[ 177 Lu]Lu-IF3和[ 225 Ac]Ac-IF3治疗的犬Gracie和人OS-33肿瘤中观察到γ-H2AX染色的时
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