CELL INTELLIGENCE · 肿瘤细胞治疗研究

恶性脑肿瘤的下一代 CAR-T 治疗：2026 年 AACR 年会最新进展

Next-generation CAR-T therapy for malignant brain tumors: latest updates from the 2026 AACR Annual Meeting.

细菌 RNA 下调肿瘤细胞系 MHC-I 并促进 NK 反应、延缓肿瘤生长

Bacterial RNA downregulates MHC-I in tumor cell lines, promoting NK response and delaying tumor growth.

中枢神经系统淋巴增殖性疾病神经影像学表现谱

Spectrum of Neuroimaging Findings in CNS Lymphoproliferative Disorders.

基于 mRNA 的实体瘤癌症疫苗的临床转化

Clinical translation of mRNA-based cancer vaccines for solid tumors.

胶质母细胞瘤中的先天免疫网络：细胞可塑性、免疫串扰及治疗意义

Innate immune networks in glioblastoma: Cellular plasticity, immune crosstalk, and therapeutic implications.

装甲 CAR-T 细胞抗耗竭：胶质母细胞瘤的工程化策略

Armoring CAR-T Cells Against Exhaustion: Engineering Strategies for Glioblastoma.

用于胶质母细胞瘤的释放抗程序性细胞死亡配体-1 抗体的 CAR 小胶质细胞样抗碳酸酐酶 IX 细胞

CAR microglia-like anti‑carbonic anhydrase IX releasing anti-programmed cell death ligand-1 antibodies for glioblastoma.

面向实体瘤的工程化 CAR-T 细胞：通过整合设计与临床转化克服微环境

Engineering CAR-T cells for solid tumors: Overcoming the microenvironment through integrated design and clinical translation.

树突状细胞疫苗治疗胶质母细胞瘤：一项比较新发与复发病例的系统评价和 Meta 分析

Dendritic Cell Vaccines for Glioblastoma: A Systematic Review and Meta-Analysis Comparing New-Onset and Recurrent Cases.

基于树突状细胞的免疫治疗可提高 GBM 患者的生存结局。结果显示，基于 DC 的免疫治疗在新诊断的 GBM 中比在复发病例中更有效。

CAR-T 细胞治疗儿童脑肿瘤：附临床试验入组标准比较分析的叙述性综述

CAR T-cell therapy in pediatric brain tumors: a narrative review with comparative analysis of clinical trial eligibility criteria.