CELL INTELLIGENCE · 肿瘤细胞治疗研究

靶向 Glypican 3 的 CAR-T 细胞分泌靶向 TROP2 的双特异性 T 细胞衔接器对肺鳞状细胞癌表现出强效疗效

Glypican 3-targeted chimeric antigen receptor T cells secreting TROP2-directed bispecific T cell engagers exhibit potent efficacy against lung squamou

本研究表明，GPC3 CAR-T。

CD4(+) 抗 TGF-β CAR-T 细胞与 CD8(+) 常规 CAR-T 细胞表现出协同抗肿瘤效应

CD4(+) anti-TGF-β CAR T cells and CD8(+) conventional CAR T cells exhibit synergistic antitumor effects.

DAP10 整合入 CAR-T 细胞通过利用内源性 NKG2D 增强对异质性肿瘤的杀伤

DAP10 integration in CAR-T cells enhances the killing of heterogeneous tumors by harnessing endogenous NKG2D.