用于乳腺癌治疗的可注射水凝胶:从肿瘤微环境响应性与主动靶向药物递送到免疫治疗与诊疗一体化
Injectable Hydrogels for Breast Cancer Therapy: From Tumor Microenvironment-Responsive and Actively Targeted Drug Delivery to Immunotherapy and Theran
乳腺癌治疗仍面临诸多挑战,包括局部复发、全身毒性、肿瘤异质性、耐药和免疫抑制。
FRONTIER PAPERS
Injectable Hydrogels for Breast Cancer Therapy: From Tumor Microenvironment-Responsive and Actively Targeted Drug Delivery to Immunotherapy and Theran
乳腺癌治疗仍面临诸多挑战,包括局部复发、全身毒性、肿瘤异质性、耐药和免疫抑制。
Chimeric antigen receptor NK cells for breast cancer immunotherapy.
乳腺癌是全球女性中最常见的恶性肿瘤,需要超越手术、化疗、放疗和内分泌治疗等传统疗法的创新治疗策略。
Evaluation of Efficacy and Safety of Chimeric Antigen Receptor-Natural Killer (CAR-NK) Cells in Breast Cancer: A Systematic Review and Meta-Analysis.
在汇总的临床前分析中,CAR-NK 相较于未处理对照和未修饰/模拟对照显著降低了肿瘤负荷(ROM 分别为 0.311 [0.22-0.44] 和 0.42 [0.33-0.53],p < 0.001)。
Peptide-based CAR-NK cells: A novel strategy for the treatment of solid tumors.
CAR-T 细胞疗法已被证明对血液系统肿瘤有效,尽管移植物抗宿主病和细胞因子释放综合征(CRS)在一定程度上限制了其应用。
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