免疫性血小板减少症的新兴治疗进展:2025 ASH 年会精选早期与关键性试验亮点
Emerging therapeutic advances for immune thrombocytopenia: highlights from selected early‑phase and pivotal trials at the 2025 ASH annual meeting.
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FRONTIER PAPERS
Emerging therapeutic advances for immune thrombocytopenia: highlights from selected early‑phase and pivotal trials at the 2025 ASH annual meeting.
Translating B-Cell and Plasma-Cell Targeting from Oncology to Autoimmunity: Modalities, Quantitative Bridging, and a Development Roadmap.
Unveiling causal immune cell-gene associations in multiple myeloma: insights from systematic reviews and Mendelian randomization analyses.
我们的研究支持 CAR-T 细胞疗法在 rrMM 患者中的疗效和安全性,ORR 为 82.2%,严重 CRS(6.3%)和神经毒性(0.9%)发生率低。这一发现还提示 BCMA/CD19 双特异性 CAR-T 细胞具有更优的 ORR,尚待临床确认。MR 分析揭示了免疫细胞、VDR 和 VHL 等基因与 MM 之间的关联,增进了我们对其病理生理学的理解。
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