基于 T 细胞的免疫治疗在妇科恶性肿瘤中的进展与障碍
Advances and obstacles of T cell-based immunotherapy in gynecological malignancies.
T细胞介导的免疫疗法通过实现对恶性细胞的精准免疫反应,彻底改变了肿瘤学。
FRONTIER PAPERS
Advances and obstacles of T cell-based immunotherapy in gynecological malignancies.
T细胞介导的免疫疗法通过实现对恶性细胞的精准免疫反应,彻底改变了肿瘤学。
An Oral PROTAC Targeting HPK1 Degradation Potentiates Anti-Solid Tumor Immunity.
造血祖细胞激酶1(HPK1)敲除已被确定为增强抗肿瘤免疫应答的有效途径。
Lyophilized lymph nodes for improved delivery of chimeric antigen receptor T cells.
淋巴结是适应性免疫系统的重要器官,协调T细胞的初始激活、活化与耐受。
Cellular Immunotherapy for Cervical Cancer: Next Therapeutics Frontiers.
我们得出结论,该领域的未来在于合理的联合策略(例如,与免疫检查点阻断联合)和下一代工程改造(例如,装甲CAR、逻辑门、异体平台),以克服生产复杂性、毒性和高成本。
A comprehensive bibliometric analysis (2000-2022) on the mapping of knowledge regarding immunotherapeutic treatments for advanced, recurrent, or metas
这项开创性研究详细呈现了 A/R/M 宫颈癌免疫治疗研究的全景。
T cell immunotherapy for cervical cancer: challenges and opportunities.
肿瘤细胞免疫治疗在临床实践中取得了令人鼓舞的疗效,为宫颈癌的治愈带来了新希望。
Generation and Functional Characterization of PLAP CAR-T Cells against Cervical Cancer Cells.
PLAP CAR T 细胞是宫颈癌以及可能其他实体瘤进一步研究的潜在候选者。
Synergistic effect of chimeric antigen receptor modified with Bcl-2 on enhanced solid tumour targeting.
我们的研究结果表明,将抗凋亡分子整合到CART细胞中可能增强其对抗实体瘤的治疗效果。
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