用 ROBO1 CAR-T 细胞靶向胶质母细胞瘤的轴突导向依赖性
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells.
此外,在成人肺至脑转移和儿童复发髓母细胞瘤的 CDX 模型中,ROBO1 CAR T 细胞在 50-100% 的小鼠中根除了肿瘤。
FRONTIER PAPERS
Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells.
此外,在成人肺至脑转移和儿童复发髓母细胞瘤的 CDX 模型中,ROBO1 CAR T 细胞在 50-100% 的小鼠中根除了肿瘤。
B7-H3 in Brain Malignancies: Immunology and Immunotherapy.
免疫检查点B7-H3(CD276)是B7家族中具有免疫调节特性的成员,最近已被确定为难治性血液癌症和实体恶性肿瘤免疫治疗的新靶点。
B cell immunity and therapeutic opportunities in brain metastases.
脑转移(BrM)源自颅外癌症,是成人中最常见的脑部恶性肿瘤。
Real-World, Evidence-Based, Retrospective Study of Patients Infused with Commercially Released Lifileucel for Advanced Melanoma.
纳入43例患者(中位年龄59岁[范围,28至79岁];54%为男性);44%有BRAF V600突变。
Long-term survival after immunotherapy and targeted therapy without chemotherapy in an elderly patient with HER2-positive gastroesophageal junction ca
HER2(3+)和PD-L1(<5%)免疫组化染色为阳性。
Neurologic Complications of Cancer and Its Treatment.
本文讨论癌症相关神经系统并发症的诊断和治疗,包括(1)脑、脊髓和软脑膜转移的诊断与管理;
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