PD-1-CD28 增强型受体与 CD19 CAR 修饰的肿瘤浸润 T 淋巴细胞在实体瘤中产生潜在抗肿瘤能力
PD-1-CD28-enhanced receptor and CD19 CAR-modified tumor-infiltrating T lymphocytes produce potential anti-tumor ability in solid tumors.
实体瘤微环境中 T 细胞扩增能力有限和功能失活,是体内应用TIL(肿瘤浸润淋巴细胞)(TILs)时面临的主要问题。
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