CELL INTELLIGENCE · 肿瘤细胞治疗研究

胶质母细胞瘤干细胞作为肿瘤记忆的载体：一种利用 TIL（肿瘤浸润淋巴细胞）的个性化免疫治疗策略

Glioblastoma stem cells as carriers of tumour memory: a strategy for personalised immunotherapy using tumour-infiltrating lymphocytes.

对流增强递送 TIL（肿瘤浸润淋巴细胞）增强原位大鼠胶质瘤模型中的瘤内分布和治疗效果

Convection-Enhanced Delivery of Tumor-Infiltrating Lymphocytes Enhances Intratumoral Distribution and Therapeutic Efficacy in an Orthotopic Rat Glioma

胶质母细胞瘤的过继性细胞疗法：从内部寻求治愈

Adoptive Cell Therapies for Glioblastoma: A Quest for Cures from Within.

GITR 激活通过逆转耗竭增强胶质母细胞瘤扩增的 TIL（肿瘤浸润淋巴细胞）的抗肿瘤免疫

GITR activation potentiates anti-tumor immunity of tumor-infiltrating lymphocytes expanded from glioblastoma by rescuing exhaustion.

自体分析揭示胶质母细胞瘤中 Vδ2(+)γδTIL 反应的患者间异质性由细胞外基质-BTN3A 轴驱动

Autologous profiling reveals inter-patient heterogeneity in Vδ2(+)γδTIL responses to glioblastoma driven by extracellular matrix-BTN3A axis.

本研究表明，V 2 + TIL 对 GB 应答的患者间异质性由细胞外基质-BTN3A 轴驱动。自体系统能有效捕捉这种异质性，为识别免疫功能和肿瘤易感性的决定因素提供了可靠平台，这些见解对于合理设计基于 TIL 的免疫疗法至关重要。

高级别胶质瘤的免疫治疗与靶向治疗：当前与未来方向

Immunotherapy and targeted therapy for high grade gliomas: current and future directions.

高级别胶质瘤是一种网络性疾病，涉及众多相互关联的分子和微环境现象，从肿瘤内在通路和抗原性到免疫识别与攻击，再到神经元对肿瘤和免疫信号的调控。新兴疗法通常同时利用其中若干交叉机制，为这些毁灭性癌症的未来临床治疗带来了希望。不适用。

TIL 治疗胶质母细胞瘤的前景

The promise of TIL therapy for glioblastoma.

TIL（肿瘤浸润淋巴细胞）来源的 CD8(+) 克隆型浸润肿瘤组织并介导胶质母细胞瘤消退

Tumor-infiltrating lymphocytes-derived CD8(+) clonotypes infiltrate the tumor tissue and mediate tumor regression in glioblastoma.

浸润胶质母细胞瘤的功能性肿瘤反应性淋巴细胞的多克隆扩增用于个体化细胞治疗

Polyclonal expansion of functional tumor-reactive lymphocytes infiltrating glioblastoma for personalized cell therapy.

新抗原免疫治疗：通过发现与创新推动肿瘤及胶质母细胞瘤治疗中的精准医学

Neoantigen-based immunotherapy: advancing precision medicine in cancer and glioblastoma treatment through discovery and innovation.