瘤内 CD38(+)CD19(+)B 细胞与胰腺导管腺癌患者不良临床结局及免疫抑制相关
Intratumoral CD38(+)CD19(+)B cells associate with poor clinical outcomes and immunosuppression in patients with pancreatic ductal adenocarcinoma.
我们发现调节性 B 细胞样 CD38⁺ B 细胞浸润是胰腺导管腺癌(PDAC)的独立预后因素。
FRONTIER PAPERS
Intratumoral CD38(+)CD19(+)B cells associate with poor clinical outcomes and immunosuppression in patients with pancreatic ductal adenocarcinoma.
我们发现调节性 B 细胞样 CD38⁺ B 细胞浸润是胰腺导管腺癌(PDAC)的独立预后因素。
Trends in Nephrology: From nihilism to targeted treatment of antibody-mediated rejection.
抗CD38抗体目前构成了治疗AMR证据最强的药物类别。
Delineating MYC-Mediated Escape Mechanisms from Conventional and T Cell-Redirecting Therapeutic Antibodies.
MYC 高表达的肿瘤细胞通过几种互不重叠的机制削弱了治疗性抗体的疗效。
Novel NKG2D-directed bispecific antibodies enhance antibody-mediated killing of malignant B cells by NK cells and T cells.
用双特异性抗体结合 NKG2D,对于直接激活细胞毒性淋巴细胞,或支持单克隆抗体或双特异性 T 细胞衔接器对其的激活,具有吸引力。
Convergent Multistage Evidence Implicates the CCR2-Artemin Immune-Inflammation Axis in Acute Myeloid Leukemia.
这项整合分析确定了CCR2-ARTN是一个机制上得到支持的免疫炎症轴,促进AML风险,提供了一个潜在的治疗靶点,并需要在原代CD62L+髓系DCs中直接验证。
Characterising how a single bout of exercise in people with myeloma affects clonal plasma cell and immune effector cell frequency in blood, and daratu
运动在体外适度提高了 daratumumab 介导的 ADCC 的疗效。
The effects of exercise training for eight weeks on immune cell characteristics among breast cancer survivors.
在乳腺癌生存者中,经过 8 周运动训练后,大多数免疫细胞特征相对稳定。
Cellular and humoral immunotherapy in children, adolescents and young adults with non-Hodgkin lymphoma.
儿童、青少年和年轻成人(CAYA)复发和/或难治性(R/R)非霍奇金淋巴瘤(NHL)的预后极差(2 年总生存期低于 25%)。
Abnormalities by Multicolor Flow Cytometry for Detection of Minimal Residual Disease in Recipients of Allo-HSCT Originating from Donors: A Cohort Stud
通过 MRD 分析检测到的 allo-HSCT 受者异常可能来源于其供者。
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