CELL INTELLIGENCE · 肿瘤细胞治疗研究

PVR 介导食管鳞状细胞癌对 IL21.CD276.CAR-T 治疗的耐药

PVR Mediates Resistance to IL21.CD276.CAR-T Therapy in Esophageal Squamous Cell Carcinoma.

晚期食管鳞状细胞癌免疫治疗的进展与挑战

Advances and challenges in immunotherapy for advanced esophageal squamous cell carcinoma.

工程化 CAR-T 来源外泌体共递送 miR-145 与细胞毒性蛋白用于靶向实体瘤治疗

Engineered CAR-T-Derived Exosomes Co-Delivering miR-145 and Cytotoxic Proteins for Targeted Solid Tumour Therapy.

靶向 B7H3 的 CAR-T 细胞在急性髓系白血病和食管鳞癌中显示出强效临床前活性

CAR T cells targeting B7H3 demonstrate potent preclinical activity against AML and ESCC.

分泌 PD-1 抗体的 c-Met 靶向 CAR-T 细胞对食管癌细胞系 ECA109 的体外与体内杀伤作用研究

Study on the in vitro and in vivo killing effects of PD-1 antibody-secreting c-Met-targeted CAR-T cells on esophageal cancer cell line ECA109.

c-Met/PD-1 CAR-T 细胞被成功构建，并表现出对 ECA109 食管癌细胞的显著体外和体内杀伤作用。

IL-21 武装的 EGFR-VHH-CAR-T 细胞疗法治疗食管鳞状细胞癌

Interleukin 21-Armed EGFR-VHH-CAR-T Cell Therapy for the Treatment of Esophageal Squamous Cell Carcinoma.

利用 NKG2D CAR-T 细胞联合放疗：食管鳞状细胞癌治疗的新策略

Harnessing NKG2D CAR-T cells with radiotherapy: a novel approach for esophageal squamous cell carcinoma treatment.

我们首次阐明了 NKG2D CAR-T 细胞在 ESCC 中的治疗疗效，以及其与放疗联合时的增强效应，为 ESCC 患者提供了一种新的治疗策略。

双特异性 c-Met/PD-1 CAR-T 细胞对实体瘤具有增强的治疗效果

Bispecific c-Met/PD-1 CAR-T Cells Have Enhanced Therapeutic Effects on Solid Tumor.

CAR-T 细胞中 CCR5 和 IL-12 共表达通过重编程实体瘤肿瘤微环境提高抗肿瘤疗效

CCR5 and IL-12 co-expression in CAR T cells improves antitumor efficacy by reprogramming tumor microenvironment in solid tumors.

消化道肿瘤免疫治疗的最新进展

Recent developments in immunotherapy for gastrointestinal tract cancers.