CELL INTELLIGENCE · 肿瘤细胞治疗研究

胶质母细胞瘤的下一代治疗：挑战与未来方向

Next-generation therapeutics for glioblastoma: Challenges and future directions.

用于实体瘤中工程化细胞治疗多重原位筛选的空间分辨可植入微装置

A spatially resolved implantable microdevice for multiplexed in situ screening of engineered cellular therapies in solid tumors.

分泌 EGFR T 细胞衔接器的靶向 B7 homolog 3 的 CAR-T 细胞用于改善胶质母细胞瘤进展控制

B7 homolog 3-targeted CAR-T cells secreting EGFR T-cell engagers for improved control of glioblastoma progression.

胶质母细胞瘤的代谢与翻译后脆弱性：二硫死亡、糖基化及对 CAR-T 治疗的启示

Metabolic and Post-Translational Vulnerabilities of Glioblastoma: Disulfidptosis, Glycosylation, and Implications for CAR-T Therapy.

经巨噬细胞靶向 EGFR(VIII) 突变胶质母细胞瘤细胞的新型嵌合抗原受体（CAR）策略

A novel Chimeric Antigen Receptor (CAR) - strategy to target EGFR(VIII)-mutated glioblastoma cells via macrophages.

本工作所描述的模型适合用于向 iPSC 来源巨噬细胞的转化，以在表达突变变体 EGFR VIII 的实体瘤中产生未来可临床应用的细胞治疗方法。

通过编码双特异性 T 细胞衔接器的溶瘤腺病毒改造微环境以实现胶质母细胞瘤中的 CAR-T 细胞免疫治疗

Enable CAR T cell immunotherapy in glioblastoma by modifying its microenvironment via oncolytic adenovirus encoding bispecific T cell engager.

胶质瘤中的 NK 细胞功能障碍：从免疫逃逸到免疫治疗

Natural killer cell dysfunction in glioma: from immune evasion to immunotherapy.

弥漫性中线胶质瘤（DMG）中分子靶向治疗诱导的免疫肽组鉴定

Identification of molecularly targeted therapy-induced immunopeptidome in diffuse midline glioma (DMG).

MTX-241F 改变了胶质瘤免疫肽组，揭示 H2B1K、脑富集免疫肽以及治疗诱导的免疫肽是免疫可见的靶点。

使用多种 CAR-T 细胞产品进行组合抗原靶向治疗胶质母细胞瘤的数学建模

Mathematical modeling of combinatorial antigen targeting with multiple CAR T-cell products for glioblastoma treatment.

胶质母细胞瘤：流行病学、分类、发病机制、诊断与治疗的当代概述——综述文章

Glioblastoma-A Contemporary Overview of Epidemiology, Classification, Pathogenesis, Diagnosis, and Treatment: A Review Article.