CELL INTELLIGENCE · 肿瘤细胞治疗研究

人类与犬骨肉瘤的整合转录组学揭示物种干性与曲贝替定敏感性

Integrated Transcriptomics of Human and Canine Osteosarcoma Reveals Species Stemness and Trabectedin Sensitivity.

阻断 FSTL1 可增强 NK 免疫在骨肉瘤治疗中的作用

Blocking FSTL1 boosts NK immunity in treatment of osteosarcoma.

骨肉瘤 HER2 靶向治疗的未来：德曲妥珠单抗阴性结果的启示

The Future of HER2-Targeted Treatment for Osteosarcoma: Lessons from the Negative Trastuzumab Deruxtecan Results.

特异性靶向肿瘤干细胞抗原 DNAJB8 的 CAR-T 细胞抗实体瘤研发

Development of CAR-T cells specifically targeting cancer stem cell antigen DNAJB8 against solid tumours.

B10 CAR-T 细胞在体外和体内对 RCC 和骨肉瘤细胞显示出特异性细胞毒性。靶向 CSC/CIC 抗原 DNAJB8 的 B10 CAR-T 细胞可能是癌和肉瘤的候选免疫疗法。

靶向肉瘤相关抗原乳头瘤病毒结合因子的 T 细胞受体工程化 T 细胞的开发

Development of T cell receptor-engineered T cells targeting the sarcoma-associated antigen papillomavirus binding factor.

hiPS 细胞衍生神经嵴细胞中 MYCN 扩增与 TP53 突变骨肉瘤模型的建立

Development of an osteosarcoma model with MYCN amplification and TP53 mutation in hiPS cell-derived neural crest cells.