CELL INTELLIGENCE · 肿瘤细胞治疗研究

scRNA+ TCR-seq 揭示 NSCLC 肿瘤微环境中双 TCR T 细胞的抗肿瘤应答

scRNA+ TCR-seq revealed dual TCR T cells antitumor response in the TME of NSCLC.

抑制 CSF-1R 和 IL-6R 可防止 cDC2s 转化为免疫无能的肿瘤诱导 DC3s，从而增强 DC 驱动的治疗潜力

Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential.

局部晚期不可切除非小细胞肺癌患者外周血淋巴细胞群体的特征

Characteristics of Peripheral Blood Lymphocyte Populations in Patients with Locally Advanced Unresectable Non-Small Cell Lung Cancer.

在局部晚期 NSCLC（IIIB-IIIC 期）患者中，免疫活性外周血细胞之间显现出的多向性变化，无疑可被视为该队列中系统性免疫紊乱（继发性免疫缺陷）的标志。