CELL INTELLIGENCE · 肿瘤细胞治疗研究

儿童脑肿瘤的局部区域和全身过继性细胞疗法：CAR-T、TCR 工程 T 细胞和 NK 细胞策略的系统综述

Locoregional and systemic adoptive cellular therapies for pediatric brain tumors: a systematic review of CAR‑T, TCR‑engineered T cells, and NK cell st

抗 CAR 免疫驱动弥漫性中线胶质瘤对 GD2-CAR-T 细胞治疗的获得性耐药

Anti-CAR Immunity Drives Acquired Therapeutic Resistance to GD2-CAR T Cell Therapy in Diffuse Midline Glioma.

儿童和年轻成人原发性中枢神经系统肿瘤的 CAR-T 细胞疗法：早期临床试验的系统综述，重点关注弥漫性中线胶质瘤

Chimeric Antigen Receptor-T Cell Therapy for Pediatric and Young Adult Primary Central Nervous System Tumors: A Systematic Review of Early Phase Clini

初步临床经验表明，针对儿童和年轻成人 CNS 肿瘤的 CAR-T 细胞疗法具有生物学活性且临床可行，其毒性特征独特但可控。

CAR-T 细胞：改善儿童肿瘤结局所缺失的一环？

CAR T cells: the missing piece needed to improve outcomes for children with cancer?

靶向 GD2 的瞬时 mRNA CAR-T 细胞在弥漫性中线胶质瘤和高级别胶质瘤模型中提供剂量调整的疗效

Transient mRNA CAR T cells targeting GD2 provide dose-adjusted efficacy against diffuse midline glioma and high-grade glioma models.

我们的结果表明，瘤内递送的瞬时 mRNA CAR-T 细胞具有实用价值，能够以明确的半衰期提供有效的肿瘤杀伤，并允许对剂量和潜在副作用进行调控。

GPC2-CAR-T 细胞对原位髓母细胞瘤异种移植瘤具有强效临床前活性

GPC2-CAR T cells have potent preclinical activity against orthotopic medulloblastoma xenografts.

工程化声遗传 EchoBack-CAR-T 细胞

Engineering sonogenetic EchoBack-CAR T cells.

FLASH 辐射重编程脂质代谢和巨噬细胞免疫并使髓母细胞瘤对 CAR-T 细胞治疗敏感

FLASH radiation reprograms lipid metabolism and macrophage immunity and sensitizes medulloblastoma to CAR-T cell therapy.

CAR-T 细胞治疗恶性胶质瘤的临床开发进展

Clinical progress in the development of CAR T cells to treat malignant glioma.

在研 CAR-T 细胞疗法的快速演进预示着胶质瘤治疗未来的巨大潜力。

作者更正：静脉与颅内 GD2-CAR-T 细胞治疗 H3K27M(+) 弥漫性中线胶质瘤

Author Correction: Intravenous and intracranial GD2-CAR T cells for H3K27M(+) diffuse midline gliomas.